Almost anyone who has suffered a miscarriage or stillbirth worries about the risk of having subsequent losses. Recent information indicates that women should look into testing after two losses when it used to be common to wait until three. This is especially important for women in their 30s and 40s. Newer studies indicate a miscarriage rate of 26-40% after a woman has suffered two losses, so earlier testing makes sense both emotionally, physically, and in many cases financially as well.

The two major clinically important categories of causes for spontaneous abortion (miscarriage) are fetal and maternal.

Fetal causes include the genetic composition of the fetus.

Human live borns have a very low percentage of chromosomal abnormalities (about 0.6% or 1 in 170). This low percentage indicates that almost all chromosomal abnormalities are lethal and aborted early in pregnancy.

The only chromosomal abnormalities (other than those involving the X and Y sex chromosomes) that might result in a human live born are trisomy 21 (three of the 21 chromosome, known as "Down's syndrome"), trisomy 18 (three of the 18 chromosome, known as "Edward's syndrome" and all die during infancy) and trisomy 13 (three of the 13 chromosome, known as "Patau syndrome" and all die during infancy).

Maternal causes include abnormalities in the "environment" in which the embryo and fetus develops. Known maternal causes related to an action of the mother are uncommon, but can include

Heavy smoking (uncommon for this to result in a loss)

Alcohol abuse (uncommon for this to result in a loss)

Irradiation or exposure to chemical toxins

Medications known to be teratogenic (cause fetal malformation)

Other maternal causes which are not related to any conscious activity of the mother or couple include

Anatomic abnormalities (typically uterine)

Hormonal imbalances (typically in progesterone)

Immunologic system errors (autoimmune and alloimmune)

Serious or life threatening maternal disease

By far the most common causes for spontaneous pregnancy loss are fetal not maternal. It is difficult for a woman with an undesired pregnancy to consciously create an unfavorable environment for the pregnancy to successfully force a miscarriage.

Deccan Fertility Clinic & Keyhole Surgery Center

1, Shankar Niwas, Plot No 117,Dadasaheb Rege Marg,Opp Shiv Sena Bhavan,

Shivaji Park,Mumbai 400 028

India

Tel: +91 22 24466633 / 24449992

Fax: +91 22 24466633

testtubebabyclinic@gmail.com

http://www.testtubebabyclinic.com